Endocrine Abstracts

Introduction: In adult patients with pituitary disease no relationship has been established between the biochemical severity of GHD and the degree of QoL impairment. Reasons may include heterogeneity of underlying pathologies, and the type of therapies received by GHD patients.Methods: The KIMS (Pfizer International Metabolic Database) database was used to focus solely on patients with non-functioning pituitary adenomas and prolactinomas treated by surge...

In children whose height is substantially below norms, behavioural and emotional problems can be experienced. When evaluating the outcomes of treatments or making treatment decisions, health related quality of life (HrQoL) should be taken into consideration. At present, no standardised HrQoL instrument for short stature youth exists. Through consensus building in five countries, the objective of this study was to develop and psychometrically test a growth-related HrQoL instrum...

Background: About 3% of all children are short statured. Clinically GH deficiency (GHD) or idiopathic short stature (ISS) is frequently diagnosed. GH (GH−) treatment, which is primarily indicated for GHD patients, is provided not only to increase height, but also to improve psychological functioning and raise health related quality of life. The present study examines these psychosocial outcomes in young German patients and their parents, and analyzes differences accordin...